A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Fertinex Online, Description, Chemistry, Ingredients - Urofollitropin
Fertinex Online, Description, Chemistry, Ingredients - Urofollitropin
DESCRIPTION
FertinexTM (urofollitropin for injection, purified) is a preparation
of highly purified Follicle Stimulating Hormone (FSH) extracted from the
urine of post-menopausal women. Purification is by immunoaffinity chromatography
using murine monoclonal antibody to human FSH. The purification process
results in a consistent FSH isoform profile, significantly enhanced specific
activity (8,500-13, 500 IU FSH/mg protein), and ³95%
purity. Each ampule of FertinexTM contains either 75 IU or
150 IU of highly purified FSH and 10 mg lactose in a sterile, lyophilized
form. If required, pH is adjusted with 0.1 M hydrochloric acid and/or
0.1 M sodium hydroxide. FertinexTM is administered by subcutaneous
injection.
FertinexTM contains an acidic, water soluble glycoprotein
biologically standardized for FSH gonadotropin activity in terms of the
Second International Reference Preparation for Human Menopausal Gonadotropins
established in September, 1964 by the Expert Committee on Biological Standards
of the World Health Organization. Negligible amounts (£
0.1 IU LH/1000 IU FSH) of leutinizing hormone (LH) activity are contained
in FertinexTM.
Therapeutic Class : Infertility.
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