A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Travasol Online, Description, Chemistry, Ingredients - Amino Acids (Injection)
Travasol Online, Description, Chemistry, Ingredients - Amino Acids (Injection)
DESCRIPTION
10% Travasol® (Amino Acid) Injection is a sterile, nonpyrogenic
hypertonic solution of essential and nonessential amino acids in a Pharmacy
Bulk Package. A Pharmacy Bulk Package is a container of a sterile preparation
for parenteral use that contains many single doses. The contents are intended
for use in a pharmacy admixture program and are restricted to the preparation
of admixtures for intravenous infusion.
The Viaflex® plastic container is fabricated from a specially
formulated polyvinyl chloride (PL 146® Plastic). Exposure
to temperatures above 25°C/77°F during transport and storage will
lead to minor losses in moisture content. Higher temperatures lead to
greater losses. It is unlikely that these minor losses will lead to clinically
significant changes within the expiration period. The amount of water
that can permeate from inside the container into the overwrap is insufficient
to affect the solution significantly. Solutions in contact with the plastic
inner bag may leach out certain chemical components from the plastic in
very small amounts; however, biological testing was supportive of the
safety of the plastic container materials.
| Each 100 mL of 10% Travasol®
(Amino Acid) Injection contains: |
| Amino acids |
|
10 g |
| Total nitrogen |
|
1.65 g |
| pH |
|
6.0 (5.0 to 7.0) |
|
(pH adjusted with glacial acetic acid and may have been adjusted
with sodium hydroxide.)
|
|
Essential Amino Acids
|
|
|
| Leucine - C6H13NO2 |
|
730 mg |
| Isoleucine - C6H13NO2 |
|
600 mg |
| Lysine( added as the hydrochloride salt) - C6H14N2O2 |
|
580 mg |
| Valine - C5H11NO2 |
|
580 mg |
| Phenylalanine - C9H11NO2 |
|
560 mg |
| Histidine - C6H9N3O2 |
|
480 mg |
| Threonine - C4H9NO3 |
|
420 mg |
| Methionine- C5H11NO2S |
|
400 mg |
| Tryptophan - C11H12N2O2 |
|
180 mg |
|
Nonessential Amino Acids
|
|
|
| Alanine - C3H7NO2 |
|
2.07 g |
| Arginine - C6H14N4O2 |
|
1.15 g |
| Glycine - C2H5NO2 |
|
1.03 g |
| Proline - C5H9NO2 |
|
680 mg |
| Serine - C3H7NO3 |
|
500 mg |
| yrosine - C9H11NO3 |
|
40 mg |
|
Anion profiles per liter*
|
|
|
| Acetate (1) |
|
88 mEq |
| Chloride (2) |
|
40 mEq |
| *Balanced by ions from amino acids. |
|
|
| (1 ) derived from pH adjustment with glacial acetic
acid |
|
|
| (2) contributed by the lysine hydrochloride |
|
|
| Osmolarity (Calc.) |
|
998 mOsmol/L |
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