A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Silvadene Indications, Dosage, Storage, Stability - Silver Sulfadiazine
Silvadene Indications, Dosage, Storage, Stability - Silver Sulfadiazine
INDICATIONS
SILVADENE
cream 1% (silver sulfadiazine) is a topical
antimicrobial
drug indicated as an adjunct
for the prevention
and treatment of wound
sepsis in patients with
second- and third-degree
burns.
DOSAGE AND ADMINISTRATION
Prompt institution of appropriate
regimens for care of the burned patient is of prime
importance and includes the control
of shock and pain. The
burn wounds are then cleansed and debrided, and silver
sulfadiazine cream
1% is applied under sterile
conditions. The burn areas
should be covered with silver
sulfadiazine cream
1% at all times. The cream
should be applied once to twice daily to a thickness of approximately
1/16 inch. Whenever necessary, the cream
should be reapplied to any areas from which it has been removed
by patient activity.
Administration may be accomplished in minimal time
because dressings are not required. However, if individual patient
requirements make dressings necessary, they may be used.
Reapply immediately after hydrotherapy.
Treatment with silver
sulfadiazine cream
1% should be continued until satisfactory healing
has occurred, or until the burn
site is ready for grafting.
The drug should not be
withdrawn from the therapeutic
regimen while there remains the possibility of infection
except if a significant adverse reaction
occurs.
HOW SUPPLIED
Silver sulfadiazine
cream 1% is available
in jars containing
- 50 g (NDC 61570-131-50)
- 400 g (NDC 61570-131-40) AND
- 1000 g (NDC 61570-131-98)
and tubes containing
- 20 g (NDC 61570-131-20) and
- 85 g (NDC 61570-131-85).
REFERENCES
1. Caffee F, Bingham H. Leukopenia and silver
sulfadiazine. J Trauma. 1982; 22: 586- 587.
2. Jarret F, Ellerbe S, Demling R. Acute leukopenia
during topical burn therapy
with silver sulfadiazine.
Amer J Surg. 1978; 135: 818- 819.
3. Kiker RG, Carvajal HF, Micak RP, Larson DL. A
controlled study of the effects of silver
sulfadiazine on
white blood
cell counts in burned children.
J Trauma. 1977; 17: 835- 836.
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