RAPTIVA Overdose, Contraindications and Information - Efalizumab

RAPTIVA Overdose, Contraindications and Information - Efalizumab

OVERDOSE

Doses up to 4 mg/kg/wk SC for 10 weeks following a conditioning (0.7 mg/kg) first dose have been administered without an observed increase in acute toxicity. The maximum administered single dose was 10 mg/kg IV. This was administered to one patient, who subsequently was admitted to the hospital for severe vomiting. In case of overdose, it is recommended that the patient be monitored for 2448 hours for any acute signs or symptoms of adverse reactions or effects and appropriate treatment instituted.

RAPTIVA should not be administered to patients with known hypersensitivity to RAPTIVA or any of its components.