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Quinine S04 Side Effects, and Drug Interactions - Quinine
SIDE EFFECTS
Thrombocytopenic purpura
may follow the administration
of quinine in sensitive
patients. Drug withdrawal
is usually followed by recovery. Cinchona alkaloids may depress
the hepatic enzyme
system that synthesizes
Vitamin K dependent factors. The hypoprothrombineuric effect
may enhance the action of warfarin and other oral
anticoagulants. Quinine may produce symptoms of cinchonism, such
as tinnitus, dizziness,
and gastrointestinal
disturbance. If ringing in the ears, deafness, skin
rash or visual
disturbances occur, the drug
should be discontinued.
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