A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Phenergan Vc Side Effects, and Drug Interactions - Promethazine HCl and Phenylephrine HCl (syrup)
Phenergan Vc Side Effects, and Drug Interactions - Promethazine HCl and Phenylephrine HCl (syrup)
SIDE EFFECTS
Promethazine
Nervous System: Sedation, sleepiness, occasional blurred vision,
dryness of mouth, dizziness; rarely: confusion, disorientation, and extrapyramidal
symptoms such as oculogyric crisis, torticollis, and tongue protrusion
(usually in association with parenteral injection or excessive dosage).
Cardiovascular: Increased or decreased blood pressure.
Dermatologic: Rash; rarely: photosensitivity.
Hematologic: Rarely: leukopenia, thrombocytopenia; agranulocytosis
(1 case).
Gastrointestinal: Nausea and vomiting.
Phenylephrine
Nervous System: Restlessness, anxiety, nervousness, and dizziness.
Cardiovascular: Hypertension (see WARNINGS).
Other: Precordial pain, respiratory distress, tremor, and weakness.
DRUG INTERACTIONS
Promethazine
The sedative action of promethazine is additive to the sedative effects
of other central nervous system depressants, including alcohol, narcotic
analgesics, sedatives, hypnotics, tricyclic antidepressants, and tranquilizers;
therefore, these agents should be avoided or administered in reduced dosage
to patients receiving promethazine.
Phenylephrine
Drug: Phenylephrine with prior administration of monoamine oxidase
inhibitors (MAOI).
Drug: Phenylephrine with tricyclic antidepressants.
Drug: Phenylephrine with ergot alkaloids.
Drug: Phenylephrine with bronchodilator sympathomimetic agents
and with epinephrine or other sympathomimetics.
Drug: Phenylephrine with atropine sulfate.
Drug: Phenylephrine with prior administration of propranolol or
other b- adrenergic blockers.
Drug: Phenylephrine with prior administration of phentolamine
or other a- adrenergic blockers.
Drug: Phenylephrine with diet preparations, such as amphetamines
or phenylpropanolamine.
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