Procalamine Online, Description, Chemistry, Ingredients - Amino Acid and Glycerin

Procalamine Online, Description, Chemistry, Ingredients - Amino Acid and Glycerin

ProcalAmine® (3% Amino Acid and 3% Glycerin Injection with Electrolytes) Protect from light until use.

ProcalAmine (3% Amino Acid and 3% Glycerin Injection with Electrolytes) is a sterile, nonpyrogenic, moderately hypertonic intravenous injection containing crystalline amino acids, a nonprotein energy substrate and maintenance electrolytes. A 1000 mL unit provides a total of 29 g of protein equivalent (4.6 g N) and 130 nonprotein calories.

All amino acids designated USP are the "L"-isomer with the exception of Glycine USP which does not have an isomer. Each 100 mL contains:

Glycerin USP (glycerol) 3.0 g

Isoleucine USP 0.21 g

Leucine USP 0.27 g

Lysine 0.22 g

(added as Lysine Acetate USP 0.31 g)

Methionine USP 0.16 g

Phenylalanine USP 0.17 g

Threonine USP 0.12 g

Tryptophan USP 0.046 g

Valine USP 0.20 g

Alanine USP 0.21 g

Glycine USP 0.42 g

Arginine USP 0.29 g

Histidine USP 0.085 g

Proline USP 0.34 g

Serine USP 0.18 g

Cysteine <0.014 g

(as Cysteine HCl•H₂O USP <0.020 g)

Sodium Acetate•3H₂O USP 0.20 g

Magnesium Acetate•4H₂O 0.054 g

Calcium Acetate•H₂O 0.026 g

Sodium Chloride USP 0.12 g

Potassium Chloride USP 0.15g

Phosphoric Acid NF 0.041 g

Potassium Metabisulfite NF (as an antioxidant) <0.05 g

Water for Injection USP qs

pH adjusted with Glacial Acetic Acid USP

pH: 6.8 (6.5-7.0), Calculated Osmolarity: 735 mOsmol/liter

Concentration of Electrolytes (mEq/liter): Sodium 35; Potassium 24.5; Calcium 3 Magnesium 5; Chloride 41; Phosphate (HPO=4) 7*; Acetate 47**

*3.5 mmole/liter; 10.9 mg% P

**Acetate is provided as inorganic acetate salts (23 mEq/liter), acetic acid (9 mEq/liter), and lysine acetate (15 mEq/liter). It is thought that acetate from lysine acetate and acetic acid, under the conditions of parenteral nutrition does not impact net acid/base balance when renal and respiratory functions are normal. Clinical experience seems to support this thinking, although confirmatory experimental evidence is not available.