A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Nebupent Indications, Dosage, Storage, Stability - Pentamidine Isethionate
Nebupent Indications, Dosage, Storage, Stability - Pentamidine Isethionate
INDICATIONS
Pentamidine Isethionate For Injection is indicated for the treatment
of pneumonia due to
Pneumocystis carinii.
DOSAGE AND ADMINISTRATION
Pentamidine isethionate should be administered I.M.
or I.V. only. The recommended regimen
for adults and children is 4 mg/ kg
once a day for 14 days. The benefits and risks of therapy
with pentamidine
isethionate for more than 14 days are not well defined.
Intramuscular Injection
The contents of one vial
(300 mg) should be dissolved in 3 mL of Sterile Water for Injection.
The calculated daily dose
should then be withdrawn and administered by deep
I.M. injection.
Intravenous Injection
The contents of one vial
should first be dissolved in 3 to 5 mL of Sterile Water for Injection
or Dextrose Injection 5%. The calculated dose
of pentamidine isethionate should then be withdrawn and diluted
further in 50 to 250 mL of Dextrose Injection 5%. The diluted I.V.
solutions containing pentamidine isethionate should be infused over
a period of 60 minutes.
Aseptic technique
should be employed in preparation
of all solutions. Parenteral drug
products should be inspected visually for particulate
matter and discoloration prior to administration. Intravenous infusion
solutions of pentamidine
isethionate at 1 mg and 2.5
mg/mL prepared in Dextrose Injection 5% are stable
at room temperature
for up to 24 hours.
HOW SUPPLIED
Pentamidine Isethionate For Injection is a sterile,
lyophilized powder supplied in a single-dose, fliptop vial
containing 300 mg of pentamidine
isethionate packaged in individual cartons (List 4548).
Store the dry product
at controlled room temperature
15° to 30° C (59° to 86° F). Protect the dry product
and reconstituted solution from light. Retain in carton until time
of use.
Discard unused portions.
Caution: Federal (USA) law
prohibits dispensing without prescription.
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