A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Optipranolol Indications, Dosage, Storage, Stability - Metipranolol
Optipranolol Indications, Dosage, Storage, Stability - Metipranolol
INDICATIONS
OptiPranolol Ophthalmic Solution is indicated in the treatment
of ocular conditions where lowering intraocular
pressure is likely
to be of therapeutic benefit; including patients with ocular
hypertension, and
patients with chronic open
angle glaucoma.
In controlled studies of patients with intraocular
pressure greater than
24 mmHg at baseline,
OptiPranolol Ophthalmic Solution reduced the average intraocular
pressure approximately
20-26%.
The onset of action
of OptiPranolol Ophthalmic Solution, as measured by a reduction
in intraocular pressure,
occurs within 30 minutes after a single administration. The maximum
effect occurs at about
2 hours. A reduction in intraocular
pressure can be demonstrated
24 hours after a single dose. Clinical studies in patients with
glaucoma treated for
up to two years indicate that an intraocular
pressure lowering effect
is maintained. In clinical
trials, OptiPranolol Ophthalmic Solution was safely used during
concomitant therapy
with pilocarpine, epinephrine
or acetazolamide.
DOSAGE AND ADMINISTRATION
The recommended dose is
one drop of OptiPranolol
Ophthalmic Solution in the affected eye(s) twice a day. If the patient’s
IOP is not at a satisfactory
level on this regimen, use of more frequent administration
or a larger dose of OptiPranolol Ophthalmic Solution is not known
to be of benefit. Concomitant therapy
to lower intraocular
pressure can be instituted.
HOW SUPPLIED
OptiPranolol (metipranolol 0.3% ophthalmic
solution) is supplied in a plastic
bottle with a controlled drop
tip and a white
plastic screw-top cap
as follows:
5 mL: NDC 24208-275-07-AB27507
10 mL: NDC 24208-275-09-AB27509
Storage: Store at controlled room
temperature, 15°-30° C (59°-86° F).
DO NOT USE IF CAP AND NECKRING
ARE NOT INTACT.
FOR OPHTHALMIC USE ONLY
Caution: Federal law
prohibits dispensing without prescription.
top
