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Niacor Side Effects, and Drug Interactions - Niacin Tablets

SIDE EFFECTS

Cardiovascular: Atrial fibrillation and other cardiac arrhythmias; orthostasis; hypotension.

Gastrointestinal: Dyspepsia; vomiting; diarrhea; peptic ulceration; jaundice; abnormal liver function tests.

Skin: Mild to severe cutaneous flushing; pruritus; hyperpigmentation; acanthosis nigricans; dry skin.

Metabolic: Decreased glucose-tolerance; hyperuricemia; gout.

Eye: Toxic amblyopia; cystoid macular edema.

Nervous System / Psychiatric: Headache.

DRUG INTERACTIONS

HMG-CoA Reductase Inhibitors: See WARNINGS, Skeletal Muscle.

Antihypertensive Therapy: Nicotinic acid may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension.

Aspirin: Concomitant aspirin may decrease the metabolic clearance of nicotinic acid. The clinical relevance of this finding is unclear.

Other: Concomitant alcohol or hot drinks may increase the side effects of flushing and pruritus and should be avoided at the time of drug ingestion.

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