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Neostigmine Online, Description, Chemistry, Ingredients - Neostigmine Methylsulfate (injection)

Neostigmine Online, Description, Chemistry, Ingredients - Neostigmine Methylsulfate (injection)

DESCRIPTION

Neostigmine Methylsulfate Injection, USP, an anticholinesterase agent, is a sterile, nonpyrogenic solution of neostigmine methylsulfate in Water for Injection intended for intramuscular (IM), intravenous (IV) or subcutaneous (SC) administration.

Neostigmine methylsulfate is chemically designated (m-hydroxyphenyl) trimethylammonium methyl sulfate dimethylcarbamate.

The empirical formula is C13H2N2O6S and the molecular weight is 334.39.

Neostigmine Methylsulfate Injection is available in 0.5 and 1 mg/mL strengths. The composition per mL is as follows:

Ingredients
mg/mL
Neostigmine methylsulfate 0.5
(1:2000)		 1
(1:1000)
Phenol 4.5 4.5
Sodium acetate 0.2 0.2
Water for Injection q. s. q. s.

Acetic acid and/or sodium hydroxide may have been added to adjust pH to approximately 5.9. Phenol is added as a preservative.

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