A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Tilade Online, Description, Chemistry, Ingredients - Nedocromil (inhalation)
Tilade Online, Description, Chemistry, Ingredients - Nedocromil (inhalation)
DESCRIPTION
Tilade (nedocromil sodium) is an inhaled anti-inflammatory agent
for the preventive
management of asthma. Nedocromil sodium
is a pyranoquinoline with the chemical
name 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid,
9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt,
and it has a molecular weight
of 415.3. The empirical
formula is C19H15NNa2O7.
Nedocromil sodium, a
yellow powder, is soluble
in water.
Chemical Class: Pyranoquinoline
Tilade Inhaler (nedocromil sodium
inhalation aerosol) is a pressurized metered-dose aerosol
suspension for oral
inhalation containing micronized nedocromil sodium
and sorbitan trioleate, as well as dichlorotetrafluoroethane and
dichlorodifluoromethane as propellants. Each Tilade canister contains
210 mg nedocromil sodium.
Each actuation meters 2.00 mg
nedocromil sodium from
the valve and delivers
1.75 mg nedocromil sodium
from the mouthpiece. Each 16.2 g canister provides at least 104
metered actuations. After 104 metered actuations, the amount delivered
per actuation may not be consistent and the unit
should be discarded.
Each Tilade Inhaler canister must be primed with 3 actuations prior
to the first use. If a canister remains unused for more than 7 days,
then it should be reprimed with 3 actuations.
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