A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Mag Sulfate Indications, Dosage, Storage, Stability - Magnesium Sulfate Injection
Mag Sulfate Indications, Dosage, Storage, Stability - Magnesium Sulfate Injection
INDICATIONS
Magnesium sulfate is indicated in the following conditions:
Convulsions (treatment) - Intravenous magnesium sulfate is indicated
for immediate control of life-threatening convulsions in the treatment
of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the
treatment of acute nephritis in children.
Hypomagnesemia (prophylaxis and treatment) - Magnesium sulfate
is indicated for replacement therapy in magnesium deficiency, especially
in acute hypomagnesemia accompanied by signs of tetany similar to those
of hypocalcemia.
Magnesium sulfate is also used to prevent or treat magnesium deficiency
in patients receiving total parenteral nutrition.
Tetany, uterine (treatment) - Magnesium sulfate is indicated in
uterine tetany as a myometriat relaxant.
DOSAGE AND ADMINISTRATION
Intramuscular: Adults and older children: For severe hypomagnesemia,
1 to 5 g (2 to 10 mL of 50% solution) daily in divided doses; administration
is repeated daily until serum levels have returned to normal. If deficiency
is not severe, 1 g (2 mL of 50% solution) can be given once or twice daily.
Serum magnesium levels should serve as a guide to continued dosage.
Intravenous: 1 to 4 g magnesium sulfate may be given intravenously
in 10% to 20% solution, but only with great caution; the rate should not
exceed 1.5 mL of 10% solution or equivalent per minute until relaxation
is obtained.
Intravenous Infusion: 4 g in 250 mL of 5% Dextrose Injection at
a rate not exceeding 3 mL per minute.
Usual Dose Range: 1 to 40 g daily.
Electrolyte Replenisher: Intramuscular 1 to 2 g in 50% solution
four times a day until serum magnesium is within normal limits.
Usual Pediatric Dose: Intramuscular 20 to 40 mg per kg of body
weight in a 20% solution repeated as necessary.
For Eclampsia: Initially 1 to 2 g in 25% or 50% solution is given
intramuscularly. Subsequently, 1 g is given every 30 minutes until relief
is obtained. The blood pressure should be monitored after each injection.
Parenteral drug products should be inspected visually for particulate
matter and discoloration prior to administration, whenever solution and
container permit.
HOW SUPPLIED
|
Product No.
|
Vial Sizes
|
|
| NDC 0517-2602-25 |
2 mL Single Dose Vial |
Boxes of 25 |
| NDC 0517-2610-25 |
10 mL Single Dose Vial |
Boxes of 25 |
| NDC 0517-2650-25 |
50 mL Single Dose Vial |
Boxes of 25 |
Store at controlled room temperature 15°- 30° C( 59°- 86°
F).
Protect from freezing. Discard unused portion.
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