A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Testred Side Effects, and Drug Interactions - Methyltestosterone
Testred Side Effects, and Drug Interactions - Methyltestosterone
SIDE EFFECTS
Endocrine and Urogenital
Female: The most common side
effects of androgen
therapy are amenorrhea
and other menstrual irregularities, inhibition
of gonadotropin secretion and virilization, including deepening
of the voice and clitoral
enlargement. The latter usually is not reversible
after androgens are discontinued. When administered to a pregnant
woman androgens cause
virilization of
external genitalia of the female
fetus.
Male: Gynecomastia, and excessive frequency
and duration of penile
erections. Oligospermia may occur at high dosages (see CLINICAL
PHARMACOLOGY).
Skin and appendages: Hirsutism, male
pattern of baldness,
and acne.
Fluid and Electrolyte Disturbances: Retention of
sodium chloride, water, potassium,
calcium and inorganic
phosphates.
Gastrointestinal: Nausea, cholestatic jaundice,
alterations in liver function
tests, rarely hepatocellular
neoplasms and peliosis
hepatis (see WARNINGS).
Hematologic: Suppression of clotting
factors II, V, VII, and X, bleeding
in patients on concomitant
anticoagulant
therapy and polycythemia.
Nervous System: Increased or decreased libido,
headache, anxiety, depression,
and generalized paresthesia.
Metabolic: Increased serum
cholesterol.
Miscellaneous: Rarely anaphylactoid reactions.
DRUG ABUSE AND DEPENDENCE
Testred Capsules are classified as a schedule
III Controlled Substance under the Anabolic Steroids Act of 1990.
DRUG INTERACTIONS
Anticoagulants: C-17 substituted derivatives of testosterone,
such as methandrostenolone, have been reported to decrease the anticoagulant
requirements of patients receiving oral
anticoagulants. Patients receiving oral anticoagulant
therapy require close
monitoring, especially when androgens are started or stopped.
Oxyphenbutazone: Concurrent administration
of oxyphenbutazone and androgens may result in elevated serum
levels of oxyphenbutazone.
Insulin: In diabetic
patients the metabolic effects of androgens may decrease blood
glucose and insulin
requirements.
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