A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Brevital Sod Side Effects, and Drug Interactions - Methohexital
Brevital Sod Side Effects, and Drug Interactions - Methohexital
SIDE EFFECTS
Side effects associated with Brevital Sodium are extensions
of pharmacologic effects and include:
Cardiovascular—Circulatory depression, thrombophlebitis,
hypotension, tachycardia, peripheral vascular collapse, and convulsions in association
with cardiorespiratory arrest
Respiratory—Respiratory depression (including apnea),
cardiorespiratory arrest, laryngospasm, bronchospasm, hiccups, and dyspnea
Neurologic—Skeletal muscle hyperactivity (twitching),
injury to nerves adjacent to injection site, and seizures
Psychiatric—Emergence delirium, restlessness, and anxiety
may occur, especially in the presence of postoperative pain
Gastrointestinal—Nausea, emesis, abdominal pain, and
liver function tests abnormal
Allergic—Erythema, pruritus, urticaria, and cases of
anaphylaxis have been reported rarely
Other—Other adverse reactions include pain at injection
site, salivation, headache, and rhinitis
DRUG ABUSE AND DEPENDENCE
Controlled Substance—Brevital Sodium is a Schedule IV drug.
Brevital Sodium may be habit-forming.
DRUG INTERACTIONS
Prior chronic administration of barbiturates or phenytoin (e.g.
for seizure disorder) appears to reduce the effectiveness of Brevital Sodium.
Barbiturates may influence the metabolism of other concomitantly used drugs,
such as phentyoin, halothane, anticoagulants, corticosteroids, ethyl alcohol,
and propylene glycol-containing solutions.
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