A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Liposyn Side Effects, and Drug Interactions - Liposyn II
Liposyn Side Effects, and Drug Interactions - Liposyn II
SIDE EFFECTS
Sepsis due to contamination of administration equipment and thrombophlebitis
due to vein irritation from concurrently administered hypertonic solutions
have been encountered. These are attributable to I.V. therapy in general
or to the type of infusion administered.
Adverse reactions directly related to fat emulsions are of two types:
(1) immediate (acute) and (2) long term (chronic). In studies of lipid
products in general, the following immediate reactions have been noted:
Allergic reactions, hyperlipemia, dyspnea, cyanosis, flushing, dizziness,
headache, sleepiness, nausea, vomiting, hyperthermia, sweating, chest
and back pain, thrombocytopenia (rarely in neonates), hypercoagulability
and transient increases in liver enzymes.
The following reactions have been noted with long-term therapy with lipid
infusions in general: Hepatomegaly, jaundice due to central lobular cholestasis,
splenomegaly, thrombocytopenia, leucopenia, transient increases in liver
function tests, overloading syndrome and deposition of brown pigment ("fat
pigment") in the reticuloendothelial tissue on the liver. The significance
of this last occurrence and its cause are unknown.
DRUG INTERACTIONS
No information provided.
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