A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Ketalar Side Effects, and Drug Interactions - Ketamine HCl
Ketalar Side Effects, and Drug Interactions - Ketamine HCl
SIDE EFFECTS
Cardiovascular
Blood pressure and
pulse rate
are frequently elevated following administration of ketamine alone.
However hypotension
and bradycardia
have been observed. Arrhythmia has also occurred.
Respiration
Although respiration
is frequently stimulated, severe depression
of respiration or apnea
may occur following rapid intravenous
administration of high doses of ketamine. Laryngospasms and other
forms of airway obstruction have occurred during ketamine anesthesia.
Eye
Diplopia and nystagmus
have been noted following ketamine administration. It also may cause
a slight elevation
in intraocular pressure
measurement.
Psychological
(See DESCRIPTION: SPECIAL NOTE.)
Neurological
In some patients, enhanced skeletal
muscle tone
may be manifested by tonic and clonic
movements sometimes resembling seizures (see DOSAGE
AND ADMINISTRATION).
Gastrointestinal
Anorexia, nausea and
vomiting have been
observed; however, this is not usually severe and allows the great
majority of patients to take
liquids by mouth shortly
after regaining consciousness
(see DOSAGE AND ADMINISTRATION).
General
Local pain and exanthema
at the injection site
have infrequently been reported. Transient erythema
and/or morbilliform
rash have also been reported.
DRUG INTERACTIONS
Prolonged recovery time
may occur if barbiturates
and/or narcotics are used concurrently with ketamine.
Ketamine is clinically compatible
with the commonly used general and local anesthetic
agents when an adequate respiratory exchange
is maintained.
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