Lymphazurine Side Effects, and Drug Interactions - Isosulfan Blue

Lymphazurine Side Effects, and Drug Interactions - Isosulfan Blue

SIDE EFFECTS

LYMPHAZURIN™ 1 % (isosulfan blue) has demonstrated a 1.5% incidence of adverse reactions. All the reactions were of an allergic type. Localized swelling at the site of administration and mild pruritus of hands, abdomen and neck have been reported within several minutes following administration of the drug.

Reports of mild to severe reactions have appeared in the literature for compounds similar to isosulfan blue. A death has been reported following the intravenous administration of a similar compound employed to estimate depth of a severe burn. Severe reactions may be manifested by edema of the face and glottis, respiratory distress or shock; such reactions may prove fatal unless promptly controlled by such emergency measures as maintenance of a clear airway and immediate use of oxygen and resuscitative drugs. Like other sensitivity phenomena, severe reactions are more likely to occur in patients with a personal or family history of bronchial asthma, significant allergies, drug reactions or previous reactions to triphenylmethane dyes.

DRUG INTERACTIONS

No information provided.