A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
H-Big Side Effects, and Drug Interactions - Hepatitis B Immune Globulin (Human)
H-Big Side Effects, and Drug Interactions - Hepatitis B Immune Globulin (Human)
SIDE EFFECTS
Seventy-six male and female volunteers received Nabi-HBTM,
Hepatitis B Immune Globulin (Human), intramuscularly in pharmacokinetics
trials. 20 The number of patients with reactions related to the administration
of Nabi-HBTM included local reactions
such as pain 9 (12%), ache 2 (3%), erythema 2 (3%), heat1( 1%), and burning
2 (3%) at the injection site, as well as systemic reactions such as headache
20 (26%), malaise 4 (5%), nausea 4 (5%), diarrhea 2 (3%) and myalgia 4
(5%). The majority of reactions were reported as mild. The following adverse
events were reported once each in pharmacokinetics trials and were probably
related to Nabi-HBTM: chills, fatigue,
lightheadedness, abdominal cramping, and retching. There were no serious
adverse events.
No anaphylactic reactions with Nabi-HBTM
have been reported. However, these reactions, although rare, have been
reported following the injection of human immune globulins.23
DRUG INTERACTIONS
Vaccination with live virus vaccines should be deferred until approximately
three months after administration of Nabi-HBTM,
Hepatitis B Immune Globulin (Human). It may be necessary to revaccinate
persons who received Nabi-HBTM shortly
after live virus vaccination.
There are no available data on concomitant use of Nabi-HBTM
and other drugs; therefore, Nabi-HBTM
should not be mixed with other drugs.
top
