Foltx Side Effects, and Drug Interactions - Folacin, cyanocobalamin & pyridoxine

Foltx Side Effects, and Drug Interactions - Folacin, cyanocobalamin & pyridoxine

SIDE EFFECTS

Allergic sensitization has been reported following both oral and parenteral administration of folacin (folic acid). Paresthesia, somnolence have been reported with pyridoxine HCl. Mild transient diarrhea, polycythemia vera, itching transitory exanthema and feeling of swelling of entire body has been associated with cyanocobalamin.

DRUG INTERACTIONS

Pyridoxine supplements should not be given to patients receiving levodopa, because the action of the latter drug is antagonized by pyridoxine. However, this vitamin may be used concurrently in patients receiving a preparation containing both carbidopa and levodopa. Concurrent use of phenytoin and folacin (folic acid) may result in decreased phenytoin effectiveness.