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Infed Side Effects, and Drug Interactions - Iron Dextran
SIDE EFFECTS
Severe/ Fatal: Anaphylactic reactions have been reported with the use of iron dextran injection; on occasions these reactions have been fatal. Such reactions, which occur most often within the first several minutes of administration have been generally characterized by sudden onset of respiratory difficulty and or cardiovascular collapse. (See BOXED WARNING and PRECAUTIONS: General , pertaining to immediate availability of epinephrine.)
Cardiovascular: Chest pain, chest tightness, shock cardiac arrest, hypotension, hypertension, tachycardia, bradycardia flushing, arrhythmias. (Flushing and hypotension may occur from too rapid injections by the intravenous route.)
Dermatologic: Urticaria, pruritus, purpura, rash, cyanosis.
Gastrointestinal: Abdominal pain, nausea, vomiting, diarrhea.
Hematologic/ lymphatic: Leucocytosis, lymphadenopathy.
Musculoskeletal/ soft tissue: Arthralgia, arthritis (may represent reactivation in patients with quiescent rheumatoid arthritis See PRECAUTIONS: General) myalgia; backache; sterile abscess, atrophy/fibrosis (intramuscular injection site); brown skin and/or underlying tissue discoloration (staining), soreness or pain at or near intramuscular injection sites; cellulitis; swelling; inflammation; local phlebitis at or near intravenous injection site.
Neurologic: Convulsions, seizures, syncope, headache, weakness, unresponsiveness paresthesia, febrile episodes, chills, dizziness, disorientation, numbness, unconsciousness.
Respiratory: Respiratory arrest, dyspnea, bronchospasm, wheezing.
Urologic: Hematuria.
Delayed reactions: Arthralgia, backache, chills, dizziness, fever headache, malaise, myalgia, nausea, vomiting (see WARNINGS).
Miscellaneous: Febrile episodes, sweating, shivering, chills, malaise, altered taste.
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