A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Inapsine Indications, Dosage, Storage, Stability - Droperidol
Inapsine Indications, Dosage, Storage, Stability - Droperidol
INDICATIONS
INAPSINE (droperidol) is indicated:
- to produce tranquilization and to reduce
the incidence of
nausea and vomiting
in surgical and diagnostic
procedures.
- for premedication, induction, and as an adjunct
in the maintenance of general and regional anesthesia.
- in neuroleptanalgesia in which INAPSINE is given concurrently
with an opioid analgesic,
such as SUBLIMAZE®
(fentanyl citrate) Injection, to aid
in producing tranquility and decreasing anxiety
and pain.
DOSAGE AND ADMINISTRATION
Dosage should be individualized. Some of the factors to
be considered in determining the dose
are age, body weight, physical
status, underlying pathological condition, use of other drugs, type
of anesthesia to
be used and the surgical
procedure involved.
Vital signs should be monitored routinely.
Usual Adult Dosage
I. Premedication - (to be appropriately modified in the
elderly, debilitated and those who have received other depressant
drugs) 2.5 to 10 mg (1 to
4 mL) may be administered intramuscularly 30 to 60 minutes preoperatively.
II. Adjunct to General Anesthesia - Induction - 2.5
mg (1 mL) per 20 to 25 pounds
may be administered (usually intravenously) along with an analgesic
and or general anesthetic.
Smaller doses may be adequate. The total amount of INAPSINE (droperidol)
administered should be titrated to obtain the desired effect
based on the individual patient's response.
Maintenance - 1.25 to 2.5 mg
(0.5 to 1 mL) usually intravenously.
III. Use without a general anesthetic
in diagnostic procedures
- Administer the usual I.M.
premedication
2.5 to 10 mg (1 to 4 mL)
30 to 60 minutes before the procedure. Additional 1.25 to 2.5 mg
(0.5 to 1 mL) amounts of INAPSINE may be administered, usually intravenously.
NOTE: When INAPSINE is used in certain procedures, such
as bronchoscopy, appropriate topical
anesthesia is still
necessary.
IV. Adjunct to regional anesthesia - 2.5 to 5 mg
(1 to 2 mL) may be administered intramuscularly or slowly intravenously
when additional sedation is required.
Usual Children's Dosage
For children two to 12 years of age, a reduced dose
as low as 1.0 to 1.5 mg (0.4
to 0.6 mL) per 20 to 25
pounds is recommended for premedication or for induction
of anesthesia.
See WARNINGS, PRECAUTIONS,
and DRUG INTERACTIONS for
use of INAPSINE with other CNS
depressants and in patients with altered response.
Parenteral drug products
should be inspected visually for particulate matter and discoloration
prior to administration, whenever solution
and container permit. If such
abnormalities are observed, the drug
should not be administered.
HOW SUPPLIED
INAPSINE (droperidol) Injection is available as:
NDC 11098-010-01, 2.5 mg/mL, 1 mL ampoules in packages of 10
NDC 11098-010-02, 2.5 mg/mL, 2 mL, ampoules in packages of 10
PROTECT FROM LIGHT.
STORE AT ROOM TEMPERATURE 15° C-25° C (59° F-77°
F).
Rx only
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