A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Benadryl Indications, Dosage, Storage, Stability - Diphenhydramine (injection)
Benadryl Indications, Dosage, Storage, Stability - Diphenhydramine (injection)
INDICATIONS
Benadryl in the injectable
form is effective in adults
and pediatric patients, other than premature
infants and neonates, for the following conditions when Benadryl
in the oral form
is impractical.
Antihistaminic
For amelioration
of allergic reactions
to blood or plasma,
in anaphylaxis as an adjunct
to epinephrine and
other standard measures
after the acute symptoms have been controlled, and for other uncomplicated
allergic conditions
of the immediate type
when oral therapy
is impossible or contraindicated.
Motion sickness
For active treatment
of motion sickness.
Antiparkinsonism
For use in parkinsonism, when oral
therapy is impossible
or contraindicated, as follows: parkinsonism
in the elderly who are unable to tolerate more potent agents; mild
cases of parkinsonism
in other age groups, and
in other cases of parkinsonism
in combination with centrally acting anticholinergic agents.
DOSAGE AND ADMINISTRATION
THIS PRODUCT IS FOR INTRAVENOUS OR
INTRAMUSCULAR ADMINISTRATION ONLY.
Benadryl in the injectable
form is indicated when
the oral form
is impractical.
Parenteral drug products
should be inspected visually for particulate matter and discoloration
prior to administration, whenever solution
and container permit.
DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO
THE NEEDS AND THE RESPONSE OF THE PATIENT.
Pediatric Patients, other than premature
infants and neonates: 5 mg/kg/24 hr
or 150 mg/m²/24 hr. Maximum daily dosage
is 300 mg. Divide into four doses, administered intravenously at
a rate generally not exceeding
25 mg/min, or deep intramuscularly.
Adults: 10 to 50 mg
intravenously at a rate
generally not exceeding 25 mg/min, or deep
intramuscularly, 100 mg if
required; maximum daily
dosage is 400 mg.
HOW SUPPLIED
Benadryl in parenteral
form is supplied as:
Benadryl Steri-Vials®
-sterile, pyrogen-free solution
containing 50 mg diphenhydramine
hydrochloride in each milliliter
of solution with 0.1
mg/mL benzethonium chloride
as a germicidal agent.
Available in 10-mL (NDC 0071-4402-10) Steri-Vials.
-sterile, pyrogen-free solution
containing 50 mg diphenhydramine
hydrochloride in each milliliter
of solution. Available in packages of twenty-five 1 mL (NDC 0071-4259-13)
Steri-Vials.
Benadryl Steri-Dose®
-sterile, pyrogen-free solution
containing 50 mg diphenhydramine
hydrochloride in a 1-mL disposable syringe
(Steri-Dose). Available in packages of ten syringes (NDC 0071-4259-45).
Benadryl Ampoule
-sterile, pyrogen-free solution
containing 50 mg diphenhydramine
hydrochloride in a 1-mL ampoule. Available in packages of ten (NDC
0071-4259-03).
Store at controlled room
temperature 15°-30°C
(59°-86°F). Protect from freezing
and light.
Rx only
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