D50W Pharmacology, Pharmacokinetics, Studies, Metabolism - Hydrous dextrose

D50W Pharmacology, Pharmacokinetics, Studies, Metabolism - Hydrous dextrose

CLINICAL PHARMACOLOGY

Dextrose Injections USP provide calories and are a source of water for hydration. They are capable of inducing diuresis depending on the clinical condition of the patient.

Dextrose is readily metabolized, may decrease losses of body protein and nitrogen, promotes glycogen deposition and decreases or prevents ketosis if sufficient doses are provided. Water is an essential constituent of all body tissues and accounts for approximately 70% of total body weight. Average normal adult daily requirements range from two to three liters (1.0 to 1.5 liters each for insensible water loss by perspiration and urine production).