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Dexone Side Effects, and Drug Interactions - Dexamethasone

Dexone Side Effects, and Drug Interactions - Dexamethasone

SIDE EFFECTS

Fluid and Electrolyte Disturbances: Sodium retention; Fluid retention; Congestive heart failure in susceptible patients: Potassium loss; Hypokalemic alkalosis & Hypertension.

Musculoskeletal: Muscle weakness; Steroid myopathy; Loss of muscle mass; Osteoporosis; Vertebral compression fractures; Aseptic necrosis of femoral and humeral heads; Pathologic fracture of long bones & Tendon rupture.

Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage. Perforation of the small and large bowel; particularly in patients with inflammatory bowel disease; Pancreatitis; Abdominal distention & Ulcerative esophagitis.

Dermatologic: Impaired wound healing; Thin fragile skin; Petechiae and ecchymoses; Erythema, increased sweating, may suppress reactions to skin tests. Other cutaneous reactions; such as allergic dermatitis, urticaria; angioneurotic edema.

Neurologic: Convulsions; Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment, Vertigo & Headache.

Endocrine: Menstrual irregularities; Development of Cushingoid state; Suppression of growth in children; Secondary adrenocortical and pituitary unresponsiveness; particularly in times of stress; as in trauma; surgery; or illness; Decreased carbohydrate tolerance; Manifestations of latent diabetes mellitus; Increased requirements for insulin or oral hypoglycemic agents in diabetes & Hirsutism.

Ophthalmic: Posterior subcapsular cataracts; increased intraocular pressure; Glaucoma & Exophthalmos.

Metabolic: Negative nitrogen balance due to protein catabolism.

Other: Hypersensitivity; Thromboembolism; Weight gain; Increased appetite; Nausea; Malaise.

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