A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Desmopress Side Effects, and Drug Interactions - Desmopressin acetate
Desmopress Side Effects, and Drug Interactions - Desmopressin acetate
SIDE EFFECTS
Infrequently, large doses of the intranasal formulations of
DDAVP and DDAVP Injection have produced transient headache, nausea, flushing
and mild abdominal cramps. These symptoms have disappeared with reduction in
dosage.
Central Diabetes Insipidus: In long-term clinical studies
in which patients with diabetes insipidus were followed for periods up to 44
months of DDAVP Tablet therapy, transient increases in AST (SGOT) no
higher than 1.5 times the upper limit of normal were occasionally observed.
Elevated AST (SGOT) returned to the normal range despite continued use of DDAVP
Tablets.
Primary Nocturnal Enuresis: The only adverse event occurring
in ³3% of patients in controlled clinical trials
with DDAVP Tablets that was probably, possibly, or remotely related to
study drug was headache (4% DDAVP, 3% placebo).
Other: The following adverse events have been reported;
however their relationship to DDAVP has not been established: abnormal thinking,
diarrhea, and edema-weight gain. See WARNINGS
for the possibility of water intoxication and hyponatremia.
DRUG INTERACTIONS
Although the pressor activity of DDAVP is very low compared
to its antidiuretic activity, large doses of DDAVP Tablets should be
used with other pressor agents only with careful patient monitoring.
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