Cortrosyn Side Effects, and Drug Interactions - Cosyntropin

Cortrosyn Side Effects, and Drug Interactions - Cosyntropin

SIDE EFFECTS

Since Cortrosyn® (cosyntropin) for injection is intended for diagnostic and not therapeutic use, adverse reactions other than a rare hypersensitivity reaction are not anticipated. To date only 3 such reactions have been reported in the literature and in each instance the patient had a pre-existing allergic disease and/or a previous reaction to natural ACTH. One investigator reported a single instance of slight whealing with splotchy erythema at the injection site. A similar but more marked reaction was also noted in the same patient following an injection of natural ACTH.

DRUG INTERACTIONS

Corticotropin may accentuate the electrolyte loss associated with diuretic therapy.