A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Cinobac Overdose, Contraindications and Information - Cinoxacin
Cinobac Overdose, Contraindications and Information - Cinoxacin
OVERDOSE
Signs and Symptoms
Symptoms following an overdose of cinoxacin may include anorexia, nausea,
vomiting, epigastric distress, and diarrhea. The severity of the epigastric
distress and the diarrhea are dose related. Headache, dizziness, insomnia,
photophobia, tinnitus, and a tingling sensation have been reported in
some patients. If other symptoms are present, they are probably secondary
to an underlying disease state, an allergic reaction, or the ingestion
of a second medication with toxicity.
Treatment
In all cases of suspected overdosage, call your regional Poison Control
Center to obtain the most up-to-date information about the treatment of
overdose. This recommendation is made because, in general, information
regarding the treatment of overdosage may change more rapidly than do
package inserts.
In managing overdosage, consider the possibility of multiple drug overdoses,
interaction among drugs, and unusual drug kinetics in your patient.
Patients who have ingested an overdose of cinoxacin should be kept well
hydrated to prevent crystalluria.
Protect the patient's airway and support ventilation and perfusion. Meticulously
monitor and maintain, within acceptable limits, the patient's vital signs,
blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal
tract may be decreased by giving activated charcoal, which in many cases,
is more effective than emesis or lavage; consider charcoal instead of,
or in addition to, gastric emptying. Repeated doses of charcoal over time
may hasten elimination of some drugs that have been absorbed. Safeguard
the patient's airway when employing gastric emptying or charcoal.
Forced diuresis, peritoneal dialysis, hemodialysis, or charcoal hemoperfusion
have not been established as beneficial for an overdose of cinoxacin.
CONTRAINDICATIONS
Cinobac is contraindicated in patients with a history of hypersensitivity
to cinoxacin or other quinolones.
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