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Pregnyl Online, Description, Chemistry, Ingredients - Chorionic Gonadotropin
DESCRIPTION
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta, is composed of an alpha and a beta sub-unit. The alpha sub-unit is essentially identical to the alpha sub-units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit of human thyroid-stimulating hormone (TSH). The beta sub-units of these hormones differ in amino acid sequence.
PREGNYL® (chorionic gonadotropin
for injection, USP) is a highly purified pyrogen-free preparation
obtained from the urine
of pregnant females.
It is standardized by a biological
assay procedure. It is available for intramuscular injection
in multiple dose
vials containing 10,000 USP Units of sterile
dried powder with 5 mg
monobasic sodium
phosphate and 4.4
mg dibasic sodium phosphate.
If required, pH is adjusted
with sodium hydroxide
and/or phosphoric acid. Each package also contains a 10 mL vial
of solvent containing: water
for injection with
0.56% sodium chloride
and 0.9% BENZYL ALCOHOL, WHICH IS NOT FOR USE IN NEWBORNS. If required,
pH is adjusted with sodium
hydroxide and/or hydrochloric
acid.
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