A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Ceredase Side Effects, and Drug Interactions - Alglucerase
Ceredase Side Effects, and Drug Interactions - Alglucerase
SIDE EFFECTS
Experience in over 1000 patients treated with Ceredase has revealed
a small number of adverse events. Some of these events were related to the route
of administration including discomfort, pruritus, burning and swelling or sterile
abscess at the site of venipuncture. The remaining experiences consisted of
slight fever, chills, abdominal discomfort, nausea or vomiting. None of these
events werejudged to require medical intervention.
Symptoms suggestive of hypersensitivity have been noted in a limited number
of patients. Onset of such symptoms has occurred during or shortly after infusions;
these symptoms have included pruritus, flushing, urticaria/angioedema (a small
number of patients have had upper airway involvement), chest discomfort, respiratory
symptoms, nausea and abdominal cramping. Hypotension has been reported to occur
during a few of these events. (See WARNINGS).
Pre-treatment with antihistamines and reduced rate of infusion has allowed
continued use of Ceredase in most patients. Additional adverse symptoms
which have been reported include: fatigue, vasomotor irritability or hot flash,
weakness, headache, light headedness, dysosmia, oral ulcerations, backache and
transient peripheral edema, menstrual abnormalities and diarrhea.
Because it contains human chorionic gonadotropin, Ceredase may cause
a false positive pregnancy test.
DRUG INTERACTIONS
No information available.
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