A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Paraplatin Online, Description, Chemistry, Ingredients - Carboplatin
Paraplatin Online, Description, Chemistry, Ingredients - Carboplatin
DESCRIPTION
PARAPLATIN ® (carboplatin for injection)
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WARNING
PARAPLATIN ® (carboplatin for injection) should be
administered under the supervision of a qualified physician
experienced in the use of cancer chemotherapeutic agents.
Appropriate management of therapy
and complications is possible only when adequate treatment
facilities are readily available.
Bone marrow
suppression
is dose related
and may be severe, resulting in infection
and/or bleeding. Anemia may be cumulative
and may require transfusion support. Vomiting is another
frequent drug-related side
effect.
Anaphylactic-like reactions to PARAPLATIN have been reported
and may occur within minutes of PARAPLATIN administration.
Epinephrine, corticosteroids, and antihistamines have been
employed to alleviate
symptoms.
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PARAPLATIN® (carboplatin aqueous solution) INJECTION is supplied as a sterile,
pyrogen-free, 10 mg/mL aqueous solution of carboplatin.
Carboplatin is a platinum
coordination compound
that is used as a cancer chemotherapeutic agent. The chemical
name for carboplatin
is platinum, diammine [1,1-cyclobutanedicarboxylato(2-)-0, 0']-,(SP-4-2), and carboplatin has the following structural formula:
Carboplatin is a crystalline
powder with the molecular
formula of C6H12N2O4Pt
and a molecular weight
of 371.25.
It is soluble in water
at a rate of approximately
14 mg/mL, and the pH of a 1% solution
is 5-7. It is virtually insoluble
in ethanol, acetone, and dimethylacetamide.
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