A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Cagluc Warnings, Precautions, Pregnancy, Nursing, Abuse - Calcium Gluconate
Cagluc Warnings, Precautions, Pregnancy, Nursing, Abuse - Calcium Gluconate
WARNINGS
For intravenous
use only. Subcutaneous or intramuscular
injection may cause
severe necrosis and
sloughing.
PRECAUTIONS
General
To avoid undesirable reactions that may follow rapid intravenous
administration of calcium
gluconate, the drug should
be given slowly, e.g., approximately 1.5 mL over a period
of one minute. When injected
intravenously, calcium gluconate should be injected
through a small needle
into a large vein in order
to avoid too rapid increase in serum
calcium and extravasation
of calcium solution
into the surrounding tissue
with resultant necrosis.
Rapid injection of
calcium gluconate may
cause vasodilation
decreased blood pressure,
bradycardia, cardiac
arrhythmias, syncope
and cardiac arrest.
Because of the danger involved in simultaneous use of calcium
salts and drugs of the digitalis
group, a digitalized patient
should not receive an intravenous
injection of a calcium
compound unless indications
are clearly defined.
Drug Interactions
The ionotropic and toxic
effects of cardiac glycosides
and calcium are synergistic
and arrhythmias may occur if these drugs are given together (particularly
when calcium is given
intravenously). Intravenous administration of calcium
should be avoided in patients receiving cardiac
glycosides; if necessary, calcium
should be given slowly in small amounts.
Calcium complexes tetracycline
antibiotics rendering them inactive. The two drugs should not be
given at the same time
orally nor should they be mixed
for parenteral administration.
Calcium Gluconate Injection has been reported to be incompatible
with intravenous
solutions containing various drugs. Published data are too varied
and/or limited to permit generalizations, and specialized references
should be consulted for specific
information.
Drug/ Laboratory Test Interactions
Transient elevations of plasma
11-hydroxy-corticosteroid levels (Glenn-Nelson technique) may occur
when intravenous
calcium is administered,
but levels return to control
values after one hour. In
addition, intravenous
calcium gluconate can produce false-negative
values for serum and urinary
magnesium.
Pregnancy Category C
Animal reproduction
studies have not been conducted with calcium
gluconate. It is also not known whether calcium
gluconate can cause fetal
harm when administered to a pregnant
woman or can affect
reproduction capacity.
Calcium gluconate should be given to a pregnant
woman only if clearly
needed.
Nursing Mothers
It is not known whether this drug
is excreted in human milk.
Because many drugs are excreted in human
milk, caution should be exercised when calcium gluconate is administered
to a nursing woman.
top
