A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Cagluc Side Effects, and Drug Interactions - Calcium Gluconate
Cagluc Side Effects, and Drug Interactions - Calcium Gluconate
SIDE EFFECTS
Patients may complain of tingling sensations, a sense
of oppression or heat waves
and a calcium or chalky
taste following the intravenous
administration of calcium
gluconate.
Rapid intravenous
injection of calcium
salts may cause vasodilation,
decreased blood pressure,
bradycardia, cardiac
arrhythmias, syncope
and cardiac arrest. Use in digitalized patients may precipitate
arrhythmias.
Local necrosis and
abscess formation
may occur with intramuscular
injection.
DRUG INTERACTIONS
The ionotropic and toxic
effects of cardiac glycosides
and calcium are synergistic
and arrhythmias may occur if these drugs are given together (particularly
when calcium is given
intravenously). Intravenous administration of calcium
should be avoided in patients receiving cardiac
glycosides; if necessary, calcium
should be given slowly in small amounts.
Calcium complexes tetracycline
antibiotics rendering them inactive. The two drugs should not be
given at the same time
orally nor should they be mixed
for parenteral administration.
Calcium Gluconate Injection has been reported to be incompatible
with intravenous
solutions containing various drugs. Published data are too varied
and/or limited to permit generalizations, and specialized references
should be consulted for specific
information.
Drug/ Laboratory Test Interactions
Transient elevations of plasma
11-hydroxy-corticosteroid levels (Glenn-Nelson technique) may occur
when intravenous
calcium is administered,
but levels return to control
values after one hour. In
addition, intravenous
calcium gluconate can produce false-negative
values for serum and urinary
magnesium.
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