Caffeine - Sodium Benzoate Overdose, Contraindications and Information - Caffeine and Sodium Benzoate

Caffeine - Sodium Benzoate Overdose, Contraindications and Information - Caffeine and Sodium Benzoate

OVERDOSE

Acute toxicity involving caffeine has been reported rarely. Mild delirium, insomnia, diuresis, dehydration, and fever commonly occur with overdosage. More serious symptoms of overdosage include cardiac arrhythmias and clonic-tonic convulsions. In adults, IV doses of 57 mg/kg of body weight and oral doses of 18.50 grams have been fatal. In one five-year-old patient, death occurred following oral ingestion of approximately 3 grams of caffeine. Convulsions may be treated with IV administration of diazepam or a barbiturate such as phenobarbital sodium.

CONTRAINDICATIONS