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Urecholine Indications, Dosage, Storage, Stability - Bethanechol

Urecholine Indications, Dosage, Storage, Stability - Bethanechol

INDICATIONS

For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.

DOSAGE AND ADMINISTRATION

Dosage must be individualized, depending on the type and severity of the condition to be treated. Preferably give the drug when the stomach is empty. If taken soon after eating, nausea and vomiting may occur.

Oral

The usual adult oral dosage ranges from 10 to 50 mg three or four times a day. The minimum effective dose is determined by giving 5 or 10 mg initially and repeating the same amount at hourly intervals until satisfactory response occurs or until a maximum of 50 mg has been given. The effects of the drug sometimes appear within 30 minutes and usually within 60 to 90 minutes. They persist for about an hour.

If necessary, the effects of the drug can be abolished promptly by atropine (see OVERDOSAGE).

HOW SUPPLIED: Urecholine® Tablets

5 mg - White, round, scored tablets in bottles of 100. Debossed OP 697
10 mg - White, round, scored tablets in bottles of 100. Debossed OP 703
25 mg - Yellow, round, scored tablets in bottles of 100. Debossed OP 704
50 mg - Yellow round, scored tablets in bottles of 100. Debossed OP 700

Dispense in a tight container as defined in the USP.

Store at controlled room temperature 15°-30°C (59°-86°F).

CAUTION: Federal law prohibits dispensing without prescription.

REFERENCES

1. Diokno, A. C.; Lapides, J., Urol. n2 23- 24, July 1977.

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