A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Celestone Online, Description, Chemistry, Ingredients - Betamethasone (Injectable Suspension)
Celestone Online, Description, Chemistry, Ingredients - Betamethasone (Injectable Suspension)
DESCRIPTION
Each mL of CELESTONE SOLUSPAN* Injectable Suspension contains: 3.0 mg
betamethasone as betamethasone sodium phosphate; 3.0 mg betamethasone
acetate; 7.1 mg dibasic sodium phosphate; 3.4 mg monobasic sodium phosphate;
0.1 mg edetate disodium; and 0.2 mg benzalkonium chloride. It is a sterile,
aqueous suspension with a pH between 6.8 and 7.2.
The formula for betamethasone sodium phosphate is C22H28FNa2O8P
with a molecular weight of 516.41. Chemically it is 9-Fluoro-11b,
17,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
21-(disodium phosphate).
The formula for betamethasone acetate is C24H31FO6with
a molecular weight of 434.50. Chemically it is 9-Fluoro-11b,
17,21-trihydroxy-16b-methylpregna-1,
4-diene-3,20-dione 21-acetate.
Betamethasone sodium phosphate is a white to practically white, odorless
powder, and is hygroscopic. It is freely soluble in water and in methanol,
but is practically insoluble in acetone and in chloroform.
Betamethasone acetate is a white to creamy white, odorless powder that
sinters and resolidifies at about 165°C, and remelts at about 200°C-220°C
with decomposition. It is practically insoluble in water, but freely soluble
in acetone, and is soluble in alcohol and in chloroform.
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