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Benzamycin Side Effects, and Drug Interactions - Erythromycin

Benzamycin Side Effects, and Drug Interactions - Erythromycin

SIDE EFFECTS

During clinical trials, 550 acne patients were studied. Of these patients, 236 were treated with

Benzamycin® Pak. The most frequently reported adverse event considered at least possibly related was dry skin (7.6%) as compared to Vehicle (3.9%). Application site reactions (stinging, burning sensation, tingling, erythema) were reported in 2.5% of patients versus 1.3% for Vehicle patients. Blepharitis, pruritus and photosensitivity reactions were reported in <2% of patients who used the dual pouch product.

Treatment Group Summaries Number of Patients (%)

BenzamycinÒ Pak

Benzamycin Ò Pak

Benzamycin® Topical Gel

BenzamycinÒ Topical Gel Vehicle

COSTART Term

N = 236

N = 153

N = 121

N = 40

DRY SKIN

18 (7.6%)

6 (3.9%)

6 (5.0%)

0

APPLICATION SITE REACTION (stinging, erythema, and burning)

6 (2.5%)

2 (1.3%)

1 (0.8%)

0

BLEPHARITIS

4 (1.7%)

1 (0.7%)

0

1 (2.5%)

PRURITUS

4 (1.7%)

2 (1.3%)

3 (2.5%)

0

PHOTOSENSITIVITY REACTION (Sunburn, stinging with sun exposure)

3 (1.3%)

0

0

0

PEELING

1 (0.5%)

1 (0.7%)

0

0

 

 

DRUG INTERACTIONS

No information available.

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