A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Bacitracin Indications, Dosage, Storage, Stability - Bacitracin
Bacitracin Indications, Dosage, Storage, Stability - Bacitracin
INDICATIONS
In accord with the statements in the WARNINGS
the use of intramuscular
bacitracin is limited to
the treatment of infants
with pneumonia and empyema
caused by staphylococci
shown to be susceptible to the drug.
To reduce the development of drug-resistant bacteria and maintain the effectiveness
of Bacitracin and other antibacterial drugs, Bacitracin should be used
only to treat or prevent infections that are proven or strongly suspected to be
caused by susceptible bacteria. When culture and susceptibility information are
available, they should be considered in selecting or modifying antibacterial therapy.
In the absence of such data, local epidemiology and susceptibility patterns
may contribute to the empiric selection of therapy.
DOSAGE AND ADMINISTRATION
TO BE ADMINISTERED INTRAMUSCULARLY ONLY
Infant dose: For infants under 2500 grams-900 units/kg/24
hours in 2 or 3 divided doses. For infants over 2500 grams-1,000 units/kg/24
hours, in 2 or 3 divided doses. Intramuscular injections of the solution
should be given in the upper outer quadrant
of the buttocks, alternating right and left
and avoiding multiple injections
in the same region because
of the transient pain
following injection.
Preparation of Solutions: Should be dissolved in sodium
chloride injection containing
2 percent procaine hydrochloride.
The concentration of the antibiotic
in the solution should not
be less than 5,000 units per mL nor more than 10,000 units per
mL.
Diluents containing parabens should not be used to reconstitute bacitracin;
cloudy solutions and precipitate
formation have occurred.
Reconstitution of the 50,000 unit
vial with 9.8 mL of diluent
will result in a concentration
of 5,000 units per mL.
Solutions are stable for one
week when stored in a refrigerator 2°to 8°C (36°to 46°
F).
HOW SUPPLIED
Sterile Bacitracin USP is available in a vial
containing 50,000 units (NDC 0009-0233-01).
Store the unreconstituted product
in a refrigerator 2° to 8°C (36° to 46°F).
Caution: Federal law prohibits
dispensing without prescription.
Rx only
Pharmacia & Upjohn Company
A subsidiary of Pharmacia Corporation
Kalamazoo, Michigan 49001, USA
Revised September 2003
top
