Cyanocobalamin Side Effects, and Drug Interactions - Cyanocobalamin

Cyanocobalamin Side Effects, and Drug Interactions - Cyanocobalamin

SIDE EFFECTS

Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (See WARNINGS).

Cardiovascular: Pulmonary edema and congestive heart failure early in treatment; peripheral vascular thrombosis.

Hematological: Polycythemia vera

Gastrointestinal: Mild transient diarrhea

Dermatological: Itching; transitory exanthema

Miscellaneous: Feeling of swelling of entire body

DRUG INTERACTIONS

Persons taking most antibiotics, methotrexate and pyrimethamine invalidate folic acid and vitamin B12 diagnostic blood assays. Colchicine para-aminosalicylic acid and heavy alcohol intake for longer than 2 weeks may produce malabsorption of vitamin B12.