A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Paregoric Warnings, Precautions, Pregnancy, Nursing, Abuse - Anhydrous Morphine
Paregoric Warnings, Precautions, Pregnancy, Nursing, Abuse - Anhydrous Morphine
WARNINGS
No information provided.
PRECAUTIONS
General
Head Injury and Increased Intracranial Pressure: The respiratory
depressant effects of narcotics and their capacity
to elevate cerebrospinal-fluid pressure may be markedly exaggerated in
the presence of head injury,
other intracranial lesions, or a preexisting increase in intracranial
pressure. Furthermore, narcotics produce additional effects that may obscure
the clinical course in patients with head
injuries.
Acute Abdominal Conditions: The administration
of morphine or other narcotics may obscure
the diagnosis or clinical
course in patients with acute
abdominal conditions.
Special-Risk Patients: Morphine should be given with caution
to certain patients, such as the elderly or debilitated and those with
severe impairment of hepatic
or renal function, hypothyroidism,
Addison's disease, and prostatic
hypertrophy or urethral
stricture.
Morphine should be used with extreme caution in patients with disorders
characterized by hypoxia,
since even usual therapeutic
doses of narcotics may decrease respiratory
drive to the point
of apnea while simultaneously
increasing airway resistance.
Hypotensive Effect: The administration
of morphine may result in
severe hypotension in
the postoperative patient
or any individual whose ability
to maintain blood pressure
has been compromised by a depleted blood volume
or the administration
of such drugs as the phenothiazines or certain anesthetics.
Supraventricular Tachycardias: Because of a possible vagolytic
action that may produce a significant
increase in the ventricular
response rate, morphine should
be used with caution in patients with atrial
flutter and other supraventricular
tachycardias.
Convulsions: Morphine may aggravate preexisting convulsions
in patients with convulsive
disorders. If dosage is escalated
substantially above recommended levels because of tolerance
development, convulsions may occur in individuals without a history
of convulsive disorders.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Paregoric has no known carcinogenic
or mutagenic potential. However no longterm animal
studies are available to support
this observation.
Usage in Pregnancy
Pregnancy Category C: Animal reproduction
studies have not been conducted with morphine. It is not known whether
morphine can cause fetal
harm when administered to a pregnant
woman or can affect
reproduction capacity. Paregoric should be given to a pregnant
woman only if clearly needed.
Nursing Mothers
Morphine appears in the milk
of nursing mothers. Caution
should be exercised when paregoric
is administered to a nursing
woman.
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