A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Amyl Nitrite Warnings, Precautions, Pregnancy, Nursing, Abuse - Amyl Nitrite
Amyl Nitrite Warnings, Precautions, Pregnancy, Nursing, Abuse - Amyl Nitrite
WARNINGS
Transient episodes of dizziness, weakness, or syncope
or other signs of cerebral ischemia
due to postural hypotension
may develop following inhalation of amyl
nitrite, particularly if the patient
is standing immobile. To hasten recovery, measures which facilitate venous
return such as head-low posture, deep
breathing and movement
of extremities may be used.
CAUTION: Amyl Nitrite is very flammable. Do not use where it might
become ignited.
PRECAUTIONS
General
Tolerance to amyl nitrite
may develop with repeated use of the drug for prolonged periods of time.
Tolerance may be minimized by beginning with the smallest effective dose
and alternating the drug with
another coronary vasodilator.
High doses of nitrites may produce methemoglobinemia, especially in individuals
with methemoglobin reductase
deficiency or other metabolic abnormality that interferes with the normal
conversion of methemoglobin
back to hemoglobin.
Patient INFORMATION
Amyl nitrite should be taken
by the patient when seated
or lying down.
Drug Interactions
Taking amyl nitrite
after drinking alcohol may
worsen side effects and may cause
severe hypotension and
cardiovascular collapse.
Carcinogenesis, Mutagenesis, Fertility Impairment
Adequate long term studies to
establish adverse carcinogenic
potential of this drug have not
been reported.
Pregnancy
Teratogenic effects: Category C. Animal studies have not
been conducted with amyl nitrite,
It is also not known whether amyl
nitrite can cause fetal
harm when administered to a pregnant
woman or can affect reproduction
capacity. Amyl nitrite should
be given to a pregnant woman
only if clearly needed.
Nursing Mothers
It is not known whether this drug
is excreted in human milk. Because
many drugs are excreted in human
milk, caution should be exercised when amyl nitrite
is administered to a nursing
woman.
Pediatric Use
Safety and effectiveness
in children have not been established.
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