A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Aclovate Online, Description, Chemistry, Ingredients - Alclometasone Dipropionate
Aclovate Online, Description, Chemistry, Ingredients - Alclometasone Dipropionate
DESCRIPTION
ACLOVATE® (alclometasone dipropionate cream) Cream
0.05%
ACLOVATE® (alclometasone dipropionate ointment) Ointment 0.05%
For Dermatologic Use Only - Not for Ophthalmic Use
ACLOVATE Cream and Ointment contain alclometasone dipropionate (7a-chloro-11b,17,21-trihydroxy-16a-methylpregna- 1,4-diene-3,20-dione-17,21-dipropionate),
a synthetic corticosteroid for topical dermatologic use. The corticosteroids
constitute a class of primarily synthetic steroids used topically as anti-inflammatory
and antipruritic agents.
Chemically, alclometasone dipropionate is C28H37ClO7 It has the following structural
formula:
Alclometasone dipropionate has the molecular weight of 521. It is a white
powder, insoluble in water, slightly soluble in propylene glycol, and
moderately soluble in hexylene glycol.
Each gram of ACLOVATE Cream contains 0.5 mg of alclometasone dipropionate
in a hydrophilic, emollient cream base of propylene glycol, white petrolatum,
cetearyl alcohol, glyceryl stearate, PEG 100 stearate, Ceteth-20, monobasic
sodium phosphate, chlorocresol, phosphoric acid, and purified water.
Each gram of ACLOVATE Ointment contains 0.5 mg of alclometasone dipropionate
in an ointment base of hexylene glycol, white wax, propylene glycol stearate,
and white petrolatum.
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