A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Differin Side Effects, and Drug Interactions - Adapalene
Differin Side Effects, and Drug Interactions - Adapalene
SIDE EFFECTS
Some adverse effects such as erythema, scaling, dryness, pruritus, and
burning will occur in 10-40% of patients. Pruritus or burning immediately
after application also occurs in approximately 20% of patients. The following
additional adverse experiences were reported in approximately 1% or less
of patients: skin irritation, burning/stinging, erythema, sunburn, and
acne flares. These are most commonly seen during the first month of therapy
and decrease in frequency and severity thereafter. All adverse effects
with use of DIFFERIN Gel during clinical trials were reversible upon discontinuation
of therapy.
DRUG INTERACTIONS
As DIFFERIN Gel has the potential to produce local irritation in some
patients, concomitant use of other potentially irritating topical products
(medicated or abrasive soaps and cleansers, soaps and cosmetics that have
a strong drying effect, and products with high concentrations of alcohol,
astringents, spices or lime) should be approached with caution. Particular
caution should be exercised in using preparations containing sulfur, resorcinol,
or salicylic acid in combination with DIFFERIN Gel. If these preparations
have been used it is advisable not to start therapy with DIFFERIN Gel
until the effects of such preparations in the skin have subsided.
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