A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Semprex D Online, Description, Chemistry, Ingredients - Acrivastine and Pseudoephedrine
Semprex D Online, Description, Chemistry, Ingredients - Acrivastine and Pseudoephedrine
DESCRIPTION
SEMPREX™- D Capsules (acrivastine and pseudoephedrine hydrochloride)
SEMPREX-D Capsules (acrivastine and pseudoephedrine HCl) are a fixed
combination product formulated
for oral administration. Acrivastine
is an antihistamine
and pseudoephedrine is a decongestant. Each capsule
contains 8 mg acrivastine and 60
mg pseudoephedrine HCl and the
inactive ingredients: lactose, magnesium
stearate and sodium
starch glycolate. The green
and white capsule shell
consists of gelatin, D& C Yellow No. 10, FD& C Green No. 3, and
titanium dioxide. The yellow
band around the capsule consists
of gelatin and D& C Yellow
No. 10. The capsules may contain one or more parabens and are printed
with edible black
and white inks.
The chemical name of acrivastine
is (E, E)-3-[6-{ l-(4-methylphenyl)-3-(1-pyrrolidinyl)-l-propenyl}-2-pyridinyl]-2-
propenoic acid; the molecular formula
is C22H24N2O2 and the molecular
weight is 348.44. As
an analog of triprolidine hydrochloride,
acrivastine is classified as an alkylamine antihistamine. Acrivastine
is an odorless, white to pale
cream crystalline
powder that is soluble
in chloroform and alcohol
and slightly soluble in water.
The chemical name of pseudoephedrine
hydrochloride is [S(
R*, R*) ~ 1,1-(methylamino) ethyl] benzenemethanol hydrochloride; the
molecular formula is C10H15NO • HCl with a molecular
weight of 201.70. Pseudoephedrine
is one of the naturally occurring dextrorotatory diastereoisomers of ephedrine
and is classified as an indirect sympathomimetic
amine. Pseudoephedrine hydrochloride occurs as odorless, fine white
to off-white crystals or powder; the drug
is soluble in water, alcohol
and chloroform.
Structural formulae for the active ingredients of SEMPREX-D Capsules are as following:
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