Acetadote Online, Description, Chemistry, Ingredients - Acetylcysteine

Acetadote Online, Description, Chemistry, Ingredients - Acetylcysteine

ACETADOTE^® (acetylcysteine) Injection

Acetylcysteine injection is an intravenous (I.V.) medication for the treatment of acetaminophen overdose. Acetylcysteine is the nonproprietary name for the N-acetyl derivative of the naturally occurring amino acid, L-cysteine (N-acetyl-L-cysteine, MAC). The compound is a whit e crystalline powder, which melts in the range of 104° to 110°C and has a very slight odor. The molecular formula of the compound is C₅H₉NO₃S, and its molecular weight is 163.2.

Acetylcysteine has the following structural formula:

Acetadote is supplied as a sterile solution in vials containing 20% w/v (200 mg/mL) acetylcysteine. The pH of the solution ranges from 6.0 to 7.5. Acetadote contains the following inactive ingredients: 0.5 mg/mL disodium edetate, sodium hydroxide (used for pH adjustment),and Sterile Water for Injection, USP.