A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Vitrasert Side Effects, and Drug Interactions - Ganciclovir
Vitrasert Side Effects, and Drug Interactions - Ganciclovir
SIDE EFFECTS
During clinical trials, the most frequent adverse events seen in patients treated with the Vitrasert Implant
involved the eye.
During the first two months following implantation, visual acuity loss of 3
lines or more, vitreous hemorrhage, and retinal detachments occurred in approximately
10-20% of patients. Cataract formation/lens opacities, macular abnormalities,
intraocular pressure spikes, optic disk/nerve changes, hyphemas and uveitis
occurred in approximately 1-5%.
Adverse events with an incidence of less than 1% were: retinopathy, anterior
chamber cell and flare, synechia, hemorrhage (other than vitreous), cotton wool
spots, keratopathy, astigmatism, endophthalmitis, microangiopathy, sclerosis,
choroiditis, chemosis, phthisis bulbi, angle closure glaucoma with anterior
chamber shallowing, vitreous detachment, vitreous traction, hypotony, severe
post-operative inflammation, retinal tear, retinal hole, corneal dellen, choroidal
folds, pellet extrusion from scleral wound, and gliosis.
DRUG INTERACTIONS
No drug interactions have been observed with the Vitrasert Implant. There is
limited experience with use of retinal tamponades in conjunction with the Vitrasert
Implant.
top
