Tao Indications, Dosage, Storage, Stability - Troleandomycin

Tao Indications, Dosage, Storage, Stability - Troleandomycin

INDICATIONS

Diplococcus pneumoniae

Pneumococcal pneumonia due to susceptible strains.

Streptococcus pyogenes

Group A beta-hemolytic streptococcal infections of the upper respiratory tract.

Injectable benzathine penicillin G is considered by the American Heart Association to be the drug of choice in the treatment and prevention of streptococcal pharyngitis and in long term prophylaxis of rheumatic fever.

Troleandomycin is generally effective in the eradication of streptococci from the nasopharynx. However, substantial data establishing the efficacy of TAO in the subsequent prevention of rheumatic fever are not available at present.

Clinical judgment based on the type of infection and its severity should determine dosage within the below listed ranges.

Adults: 250 to 500 mg 4 times a day

Children: 125 to 250 mg (3-5 mg/lb or 6.6 to 11 mg/kg) every 6 hours

When used in streptococcal infection, therapy should be continued for ten days.

TAO is supplied as:

Capsules 250 mg: Each capsule contains troleandomycin equivalent to 250 mg of oleandomycin; bottles of 100 (NDC 0049-1590-66).