A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Parnate Side Effects, and Drug Interactions - Tranylcypromine
Parnate Side Effects, and Drug Interactions - Tranylcypromine
SIDE EFFECTS
Overstimulation which may include increased anxiety, agitation and manic symptoms
is usually evidence of excessive therapeutic action. Dosage should be reduced,
or a phenothiazine tranquilizer should be administered concomitantly.
Patients may experience restlessness or insomnia; may notice some weakness,
drowsiness, episodes of dizziness or dry mouth; or may report nausea, diarrhea,
abdominal pain or constipation. Most of these effects can be relieved by lowering
the dosage or by giving suitable concomitant medication.
Tachycardia, significant anorexia, edema, palpitation, blurred vision, chills
and impotence have each been reported.
Headaches without blood pressure elevation have occurred.
Rare instances of hepatitis and skin rash have been reported.
Impaired water excretion compatible with the syndrome of inappropriate secretion
of antidiuretic hormone (SIADH) has been reported.
Tinnitus, muscle spasm, tremors, myoclonic jerks, numbness, paresthesia, urinary
retention and retarded ejaculation have been reported.
Hematologic disorders including anemia, leukopenia, agranulocytosis and thrombocytopenia
have been reported.
Post-Introduction Reports
The following are spontaneously reported adverse events temporally associated
with Parnate therapy. No clear relationship between Parnate and
these events has been established. Localized scleroderma, flare-up of cystic
acne, ataxia, confusion, disorientation, memory loss, urinary frequency, urinary
incontinence, urticaria, fissuring in corner of mouth, akinesia.
DRUG INTERACTIONS
No Information Provided.
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