Thioridazine Pharmacology, Pharmacokinetics, Studies, Metabolism - Thioridazine

Thioridazine Pharmacology, Pharmacokinetics, Studies, Metabolism - Thioridazine

CLINICAL PHARMACOLOGY

Thioridazine hydrochloride is effective in reducing excitement, hypermotility, abnormal initiative, affective tension and agitation through its inhibitory effect on psychomotor functions. Successful modification of such symptoms is the prerequisite for, and often the beginning of the process of recovery in patients exhibiting mental and emotional disturbances.

Thioridazine’s basic pharmacological activity is similar to that of other phenothiazines, but certain specific qualities have come to light which support the observation that the clinical spectrum of this drug shows significant differences from those of the other agents of this class. Minimal anti- emetic activity and minimal extrapyramidal stimulation, notably pseudoparkinsonism, are distinctive features of this drug.