A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Torecan Overdose, Contraindications and Information - Thiethylperazine
Torecan Overdose, Contraindications and Information - Thiethylperazine
OVERDOSE
Manifestations of acute
overdosage of TORECAN (thiethylperazine) can be expected to reflect
the CNS effects of the drug
and include extrapyramidal symptoms (E.P.S), confusion
and convulsions with reduced or absent reflexes, respiratory depression
and hypotension. If the patient
is conscious, vomiting should be induced
mechanically or with emetics. Gastric lavage
should be employed utilizing concurrently a cuffed endotracheal
t.b. if the patient is
unconscious to prevent
aspiration and pulmonary
complications. Maintenance of adequate pulmonary
ventilation is essential.
The use of pressor agents
intravenously may be necessary to combat hypotension. The administration
of epinephrine should
be avoided since phenothiazines
may induce a reversed epinephrine effect. The most suitable vasoconstrictive
agents are norepinephrine and phenylephrine. Fluids should be administered
intravenously to encourage diuresis. The value
of dialysis has not
been determined. If excitation occurs, barbiturates
should not be used. It should be borne in mind
that multiple agents may have been ingested.
CONTRAINDICATIONS
Severe central nervous
system (CNS) depression
and comatose states.
Use of TORECAN (thiethylperazine) is contraindicated in patients
who have demonstrated a hypersensitivity
reaction (e.g., blood
dyscrasias, jaundice) to phenothiazines.
Because severe hypotension
has been reported after the intravenous
administration of phenothiazines, this route of administration
is contraindicated.
Usage in Pregnancy
TORECAN (thiethylperazine) is contraindicated in pregnancy.
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